The Shape of Life
We study embryonic morphogenesis. Our current interests are in finding physically inspired descriptions of live-imaging data, steps towards constructing a first mechanical atlas, and connecting the physical context of an embryo to its transcriptomic dynamics.
On the developmental constraints of phenotypic variation in the fly wing(David Lubensky's opinion piece on the work)
The Dynamics of Life
We envision a new field of Transcriptomic Physics, where an interpretable and mathematically well-founded framework guides the analysis of high-dimensional and dynamical gene expression data.
The Ecology of Life
Working closely with the Kuehn Lab at UChicago we have been pursuing statistical relations between the structure of natural microbial ecosystems to their collective metabolic functions. While the work started in the context of synthetic communities of natural isolates we are now studying natural communities directly.
Predicting microbial metabolic function from genetic structure (Diane Newman and Avi Flamholz's opinion piece on the work)
The Adaptability of Life
Working closely with the Pincus Lab at UChicago we are beginning to study how cell's adapt and allocate resources during development and cancer.
The Algorithms of Life
We envision building AI models for whole genome regulation.